diff --git a/Source/Core/DolphinLib.props b/Source/Core/DolphinLib.props
index ea6c9705dc..8fcfad4353 100644
--- a/Source/Core/DolphinLib.props
+++ b/Source/Core/DolphinLib.props
@@ -650,6 +650,7 @@
     <ClInclude Include="VideoCommon\RenderState.h" />
     <ClInclude Include="VideoCommon\ShaderCache.h" />
     <ClInclude Include="VideoCommon\ShaderGenCommon.h" />
+    <ClInclude Include="VideoCommon\Spirv.h" />
     <ClInclude Include="VideoCommon\Statistics.h" />
     <ClInclude Include="VideoCommon\TextureCacheBase.h" />
     <ClInclude Include="VideoCommon\TextureConfig.h" />
@@ -1224,6 +1225,7 @@
     <ClCompile Include="VideoCommon\RenderState.cpp" />
     <ClCompile Include="VideoCommon\ShaderCache.cpp" />
     <ClCompile Include="VideoCommon\ShaderGenCommon.cpp" />
+    <ClCompile Include="VideoCommon\Spirv.cpp" />
     <ClCompile Include="VideoCommon\Statistics.cpp" />
     <ClCompile Include="VideoCommon\TextureCacheBase.cpp" />
     <ClCompile Include="VideoCommon\TextureConfig.cpp" />
diff --git a/Source/Core/VideoCommon/CMakeLists.txt b/Source/Core/VideoCommon/CMakeLists.txt
index ec8f89c829..9751df621c 100644
--- a/Source/Core/VideoCommon/CMakeLists.txt
+++ b/Source/Core/VideoCommon/CMakeLists.txt
@@ -74,6 +74,8 @@ add_library(videocommon
   ShaderCache.h
   ShaderGenCommon.cpp
   ShaderGenCommon.h
+  Spirv.cpp
+  Spirv.h
   Statistics.cpp
   Statistics.h
   TextureCacheBase.cpp
@@ -139,6 +141,7 @@ PRIVATE
   png
   xxhash
   imgui
+  glslang
 )
 
 if(_M_X86)
@@ -181,6 +184,16 @@ if(FFmpeg_FOUND)
   endif()
 endif()
 
+# Silence warnings on glslang by flagging it as a system include
+target_include_directories(videocommon
+SYSTEM PUBLIC
+  ${CMAKE_SOURCE_DIR}/Externals/glslang/glslang/Public
+SYSTEM PRIVATE
+  ${CMAKE_SOURCE_DIR}/Externals/glslang/StandAlone
+  ${CMAKE_SOURCE_DIR}/Externals/glslang/SPIRV
+  ${CMAKE_SOURCE_DIR}/Externals/glslang
+)
+
 if(MSVC)
   # Add precompiled header
   target_link_libraries(videocommon PRIVATE use_pch)
diff --git a/Source/Core/VideoCommon/Spirv.cpp b/Source/Core/VideoCommon/Spirv.cpp
new file mode 100644
index 0000000000..9819811367
--- /dev/null
+++ b/Source/Core/VideoCommon/Spirv.cpp
@@ -0,0 +1,203 @@
+// Copyright 2022 Dolphin Emulator Project
+// SPDX-License-Identifier: GPL-2.0-or-later
+
+#include "VideoCommon/Spirv.h"
+
+// glslang includes
+#include "GlslangToSpv.h"
+#include "ResourceLimits.h"
+#include "ShaderLang.h"
+#include "disassemble.h"
+
+#include "Common/FileUtil.h"
+#include "Common/Logging/Log.h"
+#include "Common/MsgHandler.h"
+#include "Common/StringUtil.h"
+#include "Common/Version.h"
+
+#include "VideoCommon/VideoBackendBase.h"
+#include "VideoCommon/VideoConfig.h"
+
+namespace
+{
+bool InitializeGlslang()
+{
+  static bool glslang_initialized = false;
+  if (glslang_initialized)
+    return true;
+
+  if (!glslang::InitializeProcess())
+  {
+    PanicAlertFmt("Failed to initialize glslang shader compiler");
+    return false;
+  }
+
+  std::atexit([]() { glslang::FinalizeProcess(); });
+
+  glslang_initialized = true;
+  return true;
+}
+
+const TBuiltInResource* GetCompilerResourceLimits()
+{
+  return &glslang::DefaultTBuiltInResource;
+}
+
+std::optional<SPIRV::CodeVector>
+CompileShaderToSPV(EShLanguage stage,
+                   std::optional<glslang::EShTargetLanguageVersion> language_version,
+                   const char* stage_filename, std::string_view source)
+{
+  if (!InitializeGlslang())
+    return std::nullopt;
+
+  std::unique_ptr<glslang::TShader> shader = std::make_unique<glslang::TShader>(stage);
+  std::unique_ptr<glslang::TProgram> program;
+  glslang::TShader::ForbidIncluder includer;
+  EProfile profile = ECoreProfile;
+  EShMessages messages = static_cast<EShMessages>(EShMsgDefault | EShMsgSpvRules);
+  int default_version = 450;
+
+  const char* pass_source_code = source.data();
+  int pass_source_code_length = static_cast<int>(source.size());
+
+  if (language_version)
+    shader->setEnvTarget(glslang::EShTargetSpv, *language_version);
+
+  shader->setStringsWithLengths(&pass_source_code, &pass_source_code_length, 1);
+
+  auto DumpBadShader = [&](const char* msg) {
+    static int counter = 0;
+    std::string filename = VideoBackendBase::BadShaderFilename(stage_filename, counter++);
+    std::ofstream stream;
+    File::OpenFStream(stream, filename, std::ios_base::out);
+    if (stream.good())
+    {
+      stream << source << std::endl;
+      stream << msg << std::endl;
+      stream << "Shader Info Log:" << std::endl;
+      stream << shader->getInfoLog() << std::endl;
+      stream << shader->getInfoDebugLog() << std::endl;
+      if (program)
+      {
+        stream << "Program Info Log:" << std::endl;
+        stream << program->getInfoLog() << std::endl;
+        stream << program->getInfoDebugLog() << std::endl;
+      }
+    }
+
+    stream << "\n";
+    stream << "Dolphin Version: " + Common::GetScmRevStr() + "\n";
+    stream << "Video Backend: " + g_video_backend->GetDisplayName();
+    stream.close();
+
+    PanicAlertFmt("{} (written to {})\nDebug info:\n{}", msg, filename, shader->getInfoLog());
+  };
+
+  if (!shader->parse(GetCompilerResourceLimits(), default_version, profile, false, true, messages,
+                     includer))
+  {
+    DumpBadShader("Failed to parse shader");
+    return std::nullopt;
+  }
+
+  // Even though there's only a single shader, we still need to link it to generate SPV
+  program = std::make_unique<glslang::TProgram>();
+  program->addShader(shader.get());
+  if (!program->link(messages))
+  {
+    DumpBadShader("Failed to link program");
+    return std::nullopt;
+  }
+
+  glslang::TIntermediate* intermediate = program->getIntermediate(stage);
+  if (!intermediate)
+  {
+    DumpBadShader("Failed to generate SPIR-V");
+    return std::nullopt;
+  }
+
+  SPIRV::CodeVector out_code;
+  spv::SpvBuildLogger logger;
+  glslang::SpvOptions options;
+
+  if (g_ActiveConfig.bEnableValidationLayer)
+  {
+    // Attach the source code to the SPIR-V for tools like RenderDoc.
+    intermediate->addSourceText(pass_source_code, pass_source_code_length);
+
+    options.generateDebugInfo = true;
+    options.disableOptimizer = true;
+    options.optimizeSize = false;
+    options.disassemble = false;
+    options.validate = true;
+  }
+
+  glslang::GlslangToSpv(*intermediate, out_code, &logger, &options);
+
+  // Write out messages
+  // Temporary: skip if it contains "Warning, version 450 is not yet complete; most version-specific
+  // features are present, but some are missing."
+  if (strlen(shader->getInfoLog()) > 108)
+    WARN_LOG_FMT(VIDEO, "Shader info log: {}", shader->getInfoLog());
+  if (strlen(shader->getInfoDebugLog()) > 0)
+    WARN_LOG_FMT(VIDEO, "Shader debug info log: {}", shader->getInfoDebugLog());
+  if (strlen(program->getInfoLog()) > 25)
+    WARN_LOG_FMT(VIDEO, "Program info log: {}", program->getInfoLog());
+  if (strlen(program->getInfoDebugLog()) > 0)
+    WARN_LOG_FMT(VIDEO, "Program debug info log: {}", program->getInfoDebugLog());
+  const std::string spv_messages = logger.getAllMessages();
+  if (!spv_messages.empty())
+    WARN_LOG_FMT(VIDEO, "SPIR-V conversion messages: {}", spv_messages);
+
+  // Dump source code of shaders out to file if enabled.
+  if (g_ActiveConfig.iLog & CONF_SAVESHADERS)
+  {
+    static int counter = 0;
+    std::string filename = StringFromFormat("%s%s_%04i.txt", File::GetUserPath(D_DUMP_IDX).c_str(),
+                                            stage_filename, counter++);
+
+    std::ofstream stream;
+    File::OpenFStream(stream, filename, std::ios_base::out);
+    if (stream.good())
+    {
+      stream << source << std::endl;
+      stream << "Shader Info Log:" << std::endl;
+      stream << shader->getInfoLog() << std::endl;
+      stream << shader->getInfoDebugLog() << std::endl;
+      stream << "Program Info Log:" << std::endl;
+      stream << program->getInfoLog() << std::endl;
+      stream << program->getInfoDebugLog() << std::endl;
+      stream << "SPIR-V conversion messages: " << std::endl;
+      stream << spv_messages;
+      stream << "SPIR-V:" << std::endl;
+      spv::Disassemble(stream, out_code);
+    }
+  }
+
+  return out_code;
+}
+}  // namespace
+
+namespace SPIRV
+{
+std::optional<CodeVector> CompileVertexShader(std::string_view source_code)
+{
+  return CompileShaderToSPV(EShLangVertex, std::nullopt, "vs", source_code);
+}
+
+std::optional<CodeVector> CompileGeometryShader(std::string_view source_code)
+{
+  return CompileShaderToSPV(EShLangGeometry, std::nullopt, "gs", source_code);
+}
+
+std::optional<CodeVector> CompileFragmentShader(std::string_view source_code)
+{
+  return CompileShaderToSPV(EShLangFragment, std::nullopt, "ps", source_code);
+}
+
+std::optional<CodeVector> CompileComputeShader(std::string_view source_code)
+{
+  return CompileShaderToSPV(EShLangCompute, std::nullopt, "cs", source_code);
+}
+}  // namespace SPIRV
diff --git a/Source/Core/VideoCommon/Spirv.h b/Source/Core/VideoCommon/Spirv.h
new file mode 100644
index 0000000000..81d1917eeb
--- /dev/null
+++ b/Source/Core/VideoCommon/Spirv.h
@@ -0,0 +1,30 @@
+// Copyright 2022 Dolphin Emulator Project
+// SPDX-License-Identifier: GPL-2.0-or-later
+
+#pragma once
+
+#include <cstddef>
+#include <optional>
+#include <string_view>
+#include <vector>
+
+#include "Common/CommonTypes.h"
+
+namespace SPIRV
+{
+// SPIR-V compiled code type
+using CodeType = u32;
+using CodeVector = std::vector<CodeType>;
+
+// Compile a vertex shader to SPIR-V.
+std::optional<CodeVector> CompileVertexShader(std::string_view source_code);
+
+// Compile a geometry shader to SPIR-V.
+std::optional<CodeVector> CompileGeometryShader(std::string_view source_code);
+
+// Compile a fragment shader to SPIR-V.
+std::optional<CodeVector> CompileFragmentShader(std::string_view source_code);
+
+// Compile a compute shader to SPIR-V.
+std::optional<CodeVector> CompileComputeShader(std::string_view source_code);
+}  // namespace SPIRV